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FOCUS ON
-
Oct 2009: Chemistry Today
- Growing challenges of API process development
in custom
manufacturing - Yves Robin,Catherine Mercier.
(Download
PDF file)
- October 2009: Isochem
receives a GMP certificate from AFSSAPS for
Vitamin E TPGS (Vitamin E, D-alpha-tocopheryl
polyethylene glycol 1000
succinate)
manufacture
Isochem
was granted a GMP compliance certificate for Vitamin
E TPGS
production
by the Drug French Authorities, AFSSAPS (Agence Française
de
Sécurité
Sanitaire des Produits de Santé). The GMP certificate
granted after an
audit
in Gennevilliers, France during July 2009 reflects the
merit of the company’s
good
manufacturing practices and guarantees value to Isochem’s
customers
who
rely on high quality Vitamin E TPGS.
Vitamin
E TPGS is a multi-task excipient used in nutraceutical
and pharmaceutical
fields.
It has proved its acknowledged utility to improve the
bioavailability of poorly
absorbed
drugs acting as a solubilizer, absorption and permeability
enhancer.
As
a water soluble compound, Vitamin E TPGS is also used
as an efficient source
of
Vitamin E, for therapeutic purposes and in the food
industry.
Over
the last two years Isochem has manufactured large quantities
of Vitamin E
TPGS
for customers worldwide thus strengthening its position
as a key partner of
the pharmaceutical market’s major actors.
- ISOCHEM invests at its
Vert-le-Petit site
The
ISOCHEM Vert-le-Petit site is a GMP site, specialized
in phosgenation,
amino
acid and peptide chemistry. It groups R&D forces and
ISOCHEM’s main
pilot
workshop. The c-GMP investment underway at the Vert-Le-Petit
pilot plant
will
equip the site with a controlled atmosphere clean room
(class 10,000)
as
well as airlocks for product, for equipment and staff,
and a washing facility
for
small equipment. ISOCHEM thus equips its pilot workshop
with a
state-of-the-art
environment for the routine production of active pharmaceutical
ingredients
(API).ISOCHEM also plans to be audited by the FDA before
the end
of
2010. This represents a nearly 600 K€ investment.
- September 2009: Participation
in the 20th International Conference on
"Organic Process Research & Development" in Lisbon from
9 to 11 September.
Oral
presentation of our NCA production technology entitled
"Production process
of
a -Amino acid N-CarboxyAnhydrides: Batch process development,
scale-up
concerns
and industrial solution".
- June 2009: Yves Robin of Isochem
shows how hydrogenation is often a key
technology
in the outsourcing of multi-step fine chemical syntheses
(Download
PDF file)
- April 2009: Heads up: The new
technical data sheet of Vitamin E TPGS
now
available (Download
PDF file)
ARCHIVES
2010 EXHIBITIONS & EVENTS
| Village de la Chimie Parc
Floral de Paris (Vincennes) |
12-13 February |
n°- |
| INFORMEX
San Francisco (USA) |
16+17-19
February |
n°1028 |
| CPhI EUROPE Paris Nord Villepinte (France) |
5-7 October |
n°- |
|
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|
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| New pilot facility in Vert-le-petit |
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